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Development of standard clinical endpoints for use in dengue interventional trials.

Development of standard clinical endpoints for use in dengue interventional trials.

May 28, 2025 Category: Blog

Dengue is a major public health problem worldwide.Although several drug candidates have been evaluated in randomized controlled trials, none has been effective and at present, early recognition of severe dengue and timely supportive care are used to reduce mortality.While the first dengue vaccine was recently licensed, and several other candidates

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Evolutionary dynamics shape two passive defensive mechanisms in Neotropical snake radiations

May 28, 2025 Category: Blog

We mapped the distribution of two defensive behaviors (balling and head hiding) of Neotropical snakes to evaluate its distribution in distinct phylogenetic groups.Balling behavior was observed in 58 out of the 167 examined species across seven families.Head hiding was observed in a total of 100 species across nine families.From the high prevalence

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One health: a comprehensive approach to improve prevention and control strategies in Leptospirosis

May 28, 2025 Category: Blog

Leptospirosis is a zoonosis caused by Leptospira spp., a spirochete that presents serovars diversity, whose prevalence, mode of transmission and circulation depend on the ecology and complex interrelation between humans, animals, and the environment in which they coexist.In animals, it affects reproduction causing economic losses and in terms of th

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